ESRs are complex -- comparative and experimental analysis from the Ast lab

A new paper from the Ast lab (Goren et al. 2006. "Comparative Analysis Identifies Exonic Splicing Regulatory Sequences -- The Complex Definition of Enhancers and Silencers" PubMed Molecular Cell) introduces the term ESR for exonic regulatory sequences and studies some of their properties. There are no surprises here, but the paper provides a key confirmation of the importance of position within the exon to ESR function.